⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840150 | 0.73 | — | — | |
| SCHEMBL19900855 | 0.73 | — | — | |
| SCHEMBL2910564 | 0.73 | — | — | |
| SCHEMBL3713171 | 0.73 | — | — | |
| SCHEMBL8587278 | 0.73 | — | — | |
| SCHEMBL5232123 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL29429357 | 0.70 | — | — | |
| SCHEMBL3204675 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL16213498 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL7962851 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974700-A | Preparation method of florfenicol fluoriding agent tetrafluoromethylethylamine | 山东国邦药业有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-119977813-A | Preparation method of difluoroethylamine | 宁夏滨河泽瑞新材料科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-115974700-A | Preparation method of florfenicol fluoriding agent tetrafluoromethylethylamine | 山东国邦药业有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115974700-A | Preparation method of florfenicol fluoriding agent tetrafluoromethylethylamine | 山东国邦药业有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115403524-A | Preparation method of 3-fluoro-pyrazole carboxylate and 3-fluoroalkyl-1-substituted pyrazole-4-carboxylic acid | 浙江省化工研究院有限公司 | 2022-11-29 | — | — | CN | disclosed |
| US-11299463-B2 | Process for the manufacture of pyrazoles or pyrimidones | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2022-04-12 | — | — | US | disclosed |
| CN-109999856-B | Catalyst for synthesizing 2, 2-difluoroethylamine and preparation method and application thereof | 陕西神光化学工业有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-112209839-A | Method for synthesizing 2, 2-difluoroethylamine by using high-boiling-point substance in R142b as raw material | 山东东岳化工有限公司 | 2021-01-12 | — | — | CN | disclosed |
| EP-3650443-A1 | CONTINUOUS FLOW SYNTHESIS OF FLUORINATED OR NON-FLUORINATED PYRAZOLES | Fujian Yongjing Technology Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |
| US-20200140390-A1 | Process for the Manufacture of Pyrazoles or Pyrimidones | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2020-05-07 | — | — | US | disclosed |
| US-8188295-B2 | Method for producing difluoromethyl-substituted pyrazole compounds | BASF SE (DE) | 2012-05-29 | — | — | US | disclosed |
| WO-2012062703-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM PROP-2-EN-1-AMINE | BAYER CROPSCIENCE AG (DE) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062702-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-18 | — | — | WO | disclosed |
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| EP-2158185-B1 | METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2011-08-17 | — | — | EP | disclosed |
| US-20110060167-A1 | Process for Preparing 2,2-Difluoroethylamine | BAYER CROPSCIENCE AG (DE) | 2011-03-10 | — | — | US | disclosed |
| WO-2011012243-A1 | METHOD FOR PRODUCING 2.2-DIFLUOROETHYLAMINE | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | WO | disclosed |
| US-20100184994-A1 | Method for Producing Difluoromethyl-Substituted Pyrazole Compounds | BASF SE (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2158185-A2 | METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED PYRAZOLE COMPOUNDS | Basf Se (DE) | 2010-03-03 | — | — | EP | disclosed |
| WO-2008152138-A2 | METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2008-12-18 | — | — | WO | disclosed |