Nervonic Acid

Nervonic Acid

SCHEMBL52329

CCCCCCCC/C=C\CCCCCCCCCCCCCC(=O)O.CCCCCCCC/C=C\CCCCCCCCCCCCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 1.00
PPARD Q03181 5/20 1.00
PPARA Q07869 5/20 1.00
F7 P08709 5/20 1.00
F3 P13726 5/20 1.00
TERT O14746 3/20 1.00
PTPN1 P18031 3/20 1.00
HSD17B10 Q99714 3/20 1.00
FABP4 P15090 3/20 1.00
TOP1 P11387 3/20 1.00
MAPT P10636 2/20 1.00
BLM P54132 2/20 1.00
LMNA P02545 2/20 1.00
ALOX15 P16050 2/20 1.00
DUSP3 P51452 2/20 1.00
CYP19A1 P11511 2/20 1.00
PTGS1 P23219 2/20 1.00
NR4A2 P43354 2/20 1.00
SIRT6 Q8N6T7 2/20 1.00
PTPN7 P35236 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22608051 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL22608057 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL22608055 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL20577298 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL25424711 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL20975500 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
Vaccenic Acid SCHEMBL25298899 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL25289881 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
Palmitoleic Acid SCHEMBL25293293 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL20577296 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174811-A High-efficiency high-purity extraction process of nervonic acid, namely cis-15-tetracosenic acid 菏泽中禾健元生物科技有限公司 2021-01-05 CN claimed
US-20240277618-A1 SOLID COMPOSITION UNIVERSITY OF CENTRAL LANCASHIRE (GB) 2024-08-22 US disclosed
US-11839687-B2 Solid composition UNIVERSITY OF CENTRAL LANCASHIRE (GB) 2023-12-12 US disclosed
CN-105503580-B A kind of extraction separation method of nervonic acid 江西青春康源制药有限公司 2017-07-21 CN disclosed
EP-1146855-A4 THERAPEUTIC DELIVERY USING COMPOUNDS SELF-ASSEMBLED INTO HIGH AXIAL RATIO MICROSTRUCTURES UNIV WASHINGTON (US) 2004-06-16 EP disclosed
EP-1146855-A1 THERAPEUTIC DELIVERY USING COMPOUNDS SELF-ASSEMBLED INTO HIGH AXIAL RATIO MICROSTRUCTURES University of Washington (US) 2001-10-24 EP disclosed
WO-2000037046-A1 THERAPEUTIC DELIVERY USING COMPOUNDS SELF-ASSEMBLED INTO HIGH AXIAL RATIO MICROSTRUCTURES UNIVERSITY OF WASHINGTON (US) 2000-06-29 WO disclosed
WO-1997018840-A2 THERAPEUTIC DELIVERY USING COMPOUNDS SELF-ASSEMBLED INTO HIGH AXIAL RATIO MICROSTRUCTURES UNIVERSITY OF WASHINGTON (US) 1997-05-29 WO disclosed
US-5194448-A Such as multiple sclerosis CRODA INTERNATIONAL PLC (GB) 1993-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839687-B2 Solid composition LIPA, LIPC, NPC1L1 PPARG 269/4885PPARD 658/4885PPARA 304/4885
US-20240277618-A1 SOLID COMPOSITION LIPA, LIPC, NPC1L1 PPARG 269/4885PPARD 658/4885PPARA 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.