Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871252 | 0.90 | CYP2C9 (0.57) | L3MBTL1CYP3A4CYP2C9HIF1AMEN1 | |
| SCHEMBL29737506 | 0.82 | L3MBTL1 (0.64) | L3MBTL1CYP3A4MEN1KMT2ACYP1A2 | |
| SCHEMBL266821 | 0.82 | L3MBTL1 (0.64) | L3MBTL1CYP3A4MEN1KMT2ACYP1A2 | |
| SCHEMBL8941738 | 0.81 | L3MBTL1 (0.56) | L3MBTL1CYP3A4CYP2C9HIF1AMEN1 | |
| SCHEMBL28235226 | 0.81 | IDO1 (0.60) | L3MBTL1CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL2586902 | 0.81 | CYP3A4 (0.53) | L3MBTL1CYP3A4HIF1AMEN1KMT2A | |
| SCHEMBL13486908 | 0.80 | MEN1 (0.49) | L3MBTL1CYP3A4CYP2C9HIF1AMEN1 | |
| SCHEMBL3581544 | 0.80 | ATM (0.49) | L3MBTL1CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL7838089 | 0.78 | MEN1 (0.48) | L3MBTL1CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL12861334 | 0.77 | CYP3A4 (0.49) | L3MBTL1CYP3A4MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |