Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.48 |
| ▸ | TYMS | P04818 | 4/20 | 0.48 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | VDR | P11473 | 4/20 | 0.48 |
| ▸ | SRC | P12931 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989236 | 0.87 | EGFR (0.44) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2995608 | 0.85 | EGFR (0.44) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2990716 | 0.85 | EGFR (0.43) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2992076 | 0.85 | EGFR (0.43) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2994297 | 0.84 | EGFR (0.42) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2997790 | 0.84 | EGFR (0.43) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2995093 | 0.83 | EGFR (0.42) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL5233169 | 0.83 | EGFR (0.45) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2986511 | 0.83 | MAPK1 (0.41) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2988708 | 0.81 | EGFR (0.41) | EGFRTYMSLTA4HVDRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |