Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | TYMS | P04818 | 6/20 | 0.45 |
| ▸ | LTA4H | P09960 | 6/20 | 0.45 |
| ▸ | VDR | P11473 | 6/20 | 0.45 |
| ▸ | SRC | P12931 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.45 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989235 | 0.88 | MAPK1 (0.42) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2995605 | 0.87 | EGFR (0.43) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2992070 | 0.87 | EGFR (0.41) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2990712 | 0.86 | EGFR (0.41) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2994293 | 0.85 | EGFR (0.40) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2995091 | 0.85 | MAPK1 (0.41) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2997787 | 0.84 | EGFR (0.40) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2986510 | 0.84 | EGFR (0.39) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL5233165 | 0.83 | EGFR (0.48) | EGFRTYMSLTA4HVDRSRC | |
| SCHEMBL2988705 | 0.82 | EGFR (0.39) | EGFRTYMSLTA4HVDRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |