Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235225 | 0.86 | CYP1A2 (0.49) | CYP1A2LOXL2ALDH1A1PDE4AADORA2A | |
| SCHEMBL29959459 | 0.86 | CYP1A2 (0.49) | CYP1A2LOXL2ALDH1A1PDE4AADORA2A | |
| SCHEMBL4872415 | 0.86 | CYP1A2 (0.49) | CYP1A2KDM4ETDP1LOXL2LMNA | |
| SCHEMBL5236887 | 0.86 | CYP1A2 (0.49) | CYP1A2KDM4ETDP1LOXL2GLA | |
| SCHEMBL5236988 | 0.86 | CYP1A2 (0.49) | CYP1A2KDM4ETDP1LOXL2GLA | |
| SCHEMBL29959944 | 0.84 | CYP1A2 (0.47) | CYP1A2LOXL2LMNAALDH1A1HPGD | |
| SCHEMBL5234356 | 0.84 | CYP1A2 (0.47) | CYP1A2LOXL2LMNAALDH1A1HPGD | |
| SCHEMBL4872056 | 0.84 | CYP1A2 (0.55) | CYP1A2KDM4ELOXL2LMNANAPRT | |
| SCHEMBL5231886 | 0.83 | MGAM (0.53) | CYP1A2KDM4ETSHRLOXL2MGAM | |
| SCHEMBL5235242 | 0.83 | CYP1A2 (0.46) | CYP1A2LOXL2ALDH1A1FAAHPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397364-B1 | NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | LILLY CO ELI (US) | 2007-07-25 | — | — | EP | disclosed |