Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947886 | 0.88 | LMNA (0.55) | LMNAGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL191353 | 0.88 | LMNA (0.55) | LMNAGAAL3MBTL1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL1835887 | 0.86 | LMNA (0.53) | LMNAGAAL3MBTL1MAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL23535368 | 0.81 | DPP7 (0.41) | EPHX2EPHX1 | |
| Trifluoroacetic Acid SCHEMBL26599559 | 0.79 | EPHX2 (0.47) | EPHX2EPHX1 | |
| SCHEMBL3285103 | 0.79 | LMNA (0.50) | LMNAGAAL3MBTL1MAPTEPHX2 | |
| Trifluoroacetic Acid SCHEMBL6325300 | 0.78 | CYP1A2 (0.44) | ALDH1A1EPHX2EPHX1 | |
| SCHEMBL18711425 | 0.78 | KDM4E (0.39) | RORCEPHX2EPHX1 | |
| SCHEMBL14239713 | 0.78 | CHRM1 (0.46) | LMNAGAAL3MBTL1MAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL16039131 | 0.77 | DPP8 (0.46) | LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-A2 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005121145-A2 | OCTAHYDRO-PYRROLO[3,4-C] DERIVATIVES AND THEIR USE AS ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-22 | — | — | WO | disclosed |