Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.46 |
| ▸ | MPO | P05164 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233106 | 0.99 | HTR1A (0.47) | HTR1AMPOSLC6A4 | |
| SCHEMBL5235551 | 0.99 | HTR1A (0.47) | HTR1AMPOSLC6A4 | |
| Hydrochloric Acid SCHEMBL5235744 | 0.98 | HTR1A (0.46) | HTR1AMPOSLC6A4 | |
| SCHEMBL5236560 | 0.97 | HTR1A (0.48) | HTR1AMPOSLC6A4 | |
| SCHEMBL5234113 | 0.97 | HTR1A (0.48) | HTR1AMPOSLC6A4 | |
| SCHEMBL5233867 | 0.94 | HTR1A (0.52) | HTR1AMPOSLC6A4 | |
| SCHEMBL5233437 | 0.88 | HTR1A (0.54) | HTR1ASLC6A4 | |
| SCHEMBL5239419 | 0.88 | HTR1A (0.49) | HTR1ASLC6A4 | |
| SCHEMBL5234655 | 0.88 | HTR1A (0.49) | HTR1ASLC6A4 | |
| SCHEMBL5233813 | 0.88 | HTR1A (0.49) | HTR1AMPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537122-B9 | ANTIDEPRESSANT INDOLEALKYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXAN METHYLAMINES | WYETH CORP (US) | 2007-10-31 | — | — | EP | claimed |
| EP-1537122-B1 | ANTIDEPRESSANT INDOLEALKYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXAN METHYLAMINES | WYETH CORP (US) | 2007-08-22 | — | — | EP | claimed |