Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 16/20 | 0.59 |
| ▸ | CALML3 | P27482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233962 | 0.90 | MAOA (0.58) | MAOACALML3CYP3A4CYP2D6MAOB | |
| SCHEMBL4017450 | 0.86 | MAOA (0.59) | MAOACALML3CYP3A4CYP2D6MAOB | |
| SCHEMBL5232210 | 0.86 | MAOA (0.80) | MAOACYP3A4CYP2D6MAOB | |
| SCHEMBL4017577 | 0.86 | MAOA (0.55) | MAOACALML3 | |
| SCHEMBL4013083 | 0.86 | MAOA (0.58) | MAOACALML3MAOB | |
| SCHEMBL14525410 | 0.85 | MAOA (0.56) | MAOACALML3CYP3A4CYP2D6MAOB | |
| SCHEMBL5657198 | 0.85 | MAOA (0.55) | MAOACALML3CYP3A4CYP2D6MAOB | |
| SCHEMBL4017100 | 0.85 | MAOA (0.56) | MAOAMAOB | |
| SCHEMBL13939808 | 0.85 | MAOA (0.80) | MAOACYP3A4CYP2D6MAOB | |
| SCHEMBL5658036 | 0.84 | MAOA (0.54) | MAOACALML3CYP3A4CYP2D6MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286998-B2 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | EP | disclosed |
| US-7141583-B2 | Oxazolidinone derivatives with antibiotic activity | ASTRAZENECA AB (SE) | 2006-11-28 | — | — | US | disclosed |
| US-20030216373-A1 | Oxazolidinone derivatives with antibiotic activity | ASTRAZENECA AB (SE) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216373-A1 | Oxazolidinone derivatives with antibiotic activity | STS, SULT1E1, OXA1L | MAOA 2239/4885CALML3 4326/4885CYP3A4 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.