Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13480613 | 0.69 | TACR2 (0.63) | TACR2CRHR1 | |
| SCHEMBL14591633 | 0.66 | PDE2A (0.52) | TACR2CRHR1 | |
| SCHEMBL5233264 | 0.65 | TACR2 (0.50) | TACR2CRHR1 | |
| SCHEMBL20628685 | 0.65 | TACR2 (0.50) | TACR2CRHR1 | |
| SCHEMBL3179740 | 0.61 | PDE2A (0.44) | TACR2CRHR1 | |
| SCHEMBL17164736 | 0.59 | NNMT (0.40) | TACR2CRHR1 | |
| SCHEMBL7278594 | 0.58 | DYRK1A (0.54) | — | |
| SCHEMBL18836510 | 0.58 | RPS6KA2 (0.48) | — | |
| SCHEMBL18774086 | 0.57 | NNMT (0.48) | — | |
| SCHEMBL2256332 | 0.57 | TACR2 (0.45) | TACR2CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368094-B1 | 4-(2-BUTYLAMINO)-2,7-DIMETHYL-8-(2-METHYL-6-METHOXYPYRID-3-YL) PYRAZOLO- 1,5-A|-1,3,5-TRIAZINE, ITS ENANTIOMERS AND PHARMACEUTICALLY ACCEPTABLE SALTS AS CORTICOTROPIN RELEASING FACTOR RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2007-02-28 | — | — | EP | disclosed |