Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.41 |
| ▸ | CCND1 | P24385 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30233822 | 0.88 | CDK4 (0.42) | CDK4CCND1SLC6A2DRD2SLC6A4 | |
| SCHEMBL30704384 | 0.83 | CDK4 (0.41) | CDK4CCND1TSHRLMNAHTR2A | |
| SCHEMBL30233726 | 0.82 | CDK4 (0.47) | CDK4CCND1SLC6A2ALDH1A1TSHR | |
| SCHEMBL3576716 | 0.82 | CDK4 (0.47) | CDK4CCND1SLC6A2ALDH1A1TSHR | |
| SCHEMBL14837866 | 0.81 | CDK4 (0.37) | CDK4CCND1SLC6A2TDP1ALDH1A1 | |
| SCHEMBL5557186 | 0.81 | HTR1B (0.45) | CDK4CCND1SLC6A4LMNAHTR2A | |
| SCHEMBL30388872 | 0.79 | CDK4 (0.43) | CDK4CCND1ALDH1A1TP53MAPK1 | |
| SCHEMBL7743545 | 0.78 | CDK4 (0.37) | CDK4CCND1SLC6A2CYP3A4MAPK1 | |
| SCHEMBL7987460 | 0.77 | CDK4 (0.42) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL31276881 | 0.77 | CDK4 (0.39) | CDK4CCND1SLC6A2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829872-B1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | NISSAN CHEMICAL IND LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-1829872-A1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |