Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.37 |
| ▸ | CCND1 | P24385 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236935 | 0.78 | CDK4 (0.41) | CDK4CCND1CYP3A4MAPK1NOTUM | |
| SCHEMBL5557186 | 0.76 | HTR1B (0.45) | CDK4CCND1SLC6A4LMNAKMT2A | |
| SCHEMBL30233822 | 0.76 | CDK4 (0.42) | CDK4CCND1NOTUMSLC6A4SLC6A2 | |
| SCHEMBL30704384 | 0.75 | CDK4 (0.41) | CDK4CCND1NOTUMLMNAKMT2A | |
| SCHEMBL30388872 | 0.74 | CDK4 (0.43) | CDK4CCND1MAPK1NOTUMKMT2A | |
| SCHEMBL14837866 | 0.73 | CDK4 (0.37) | CDK4CCND1NOTUMSLC6A4SLC6A2 | |
| SCHEMBL30233726 | 0.73 | CDK4 (0.47) | CDK4CCND1NOTUMSLC6A4SLC6A2 | |
| SCHEMBL3576716 | 0.73 | CDK4 (0.47) | CDK4CCND1NOTUMSLC6A4SLC6A2 | |
| SCHEMBL7987460 | 0.73 | CDK4 (0.42) | CDK4CCND1NOTUMLMNAKMT2A | |
| SCHEMBL31276881 | 0.72 | CDK4 (0.39) | CDK4CCND1CYP1A2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423813-B1 | FROM PHENOLIC COMPOUNDS | TEIJIN LIMITED (JP) | 2002-07-23 | — | — | US | disclosed |
| US-5993971-A | TRANSPARENT SUBSTRATE IS MADE OF A RESIN MATERIAL MAINLY CONSISTING OF A POLYCARBONATE RESIN THAT CONTAINS NO MORE THAN 4 WT % OF LOW MOLECULAR WEIGHT FRACTIONS IN ORDER TO AVOID A DOUBLE REFRACTION | SONY CORPORATION (JP) | 1999-11-30 | — | — | US | disclosed |