Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5635271 | 0.99 | LCK (0.46) | LCKEGFRSRCZAP70TRPV1 | |
| SCHEMBL5695227 | 0.74 | ADRA2A (0.44) | LCKEGFRSRCZAP70TRPV1 | |
| SCHEMBL5695226 | 0.74 | LCK (0.57) | LCKEGFRSRCZAP70ADRA2A | |
| SCHEMBL4161711 | 0.72 | LCK (0.47) | LCKEGFRSRCZAP70TRPV1 | |
| Hydrochloric Acid SCHEMBL6501404 | 0.72 | ADRA2A (0.43) | LCKEGFRSRCZAP70TRPV1 | |
| SCHEMBL3955064 | 0.72 | LCK (0.49) | LCKEGFRSRCZAP70TRPV1 | |
| Hydrochloric Acid SCHEMBL4055527 | 0.71 | LCK (0.48) | LCKEGFRSRCZAP70TRPV1 | |
| SCHEMBL5240162 | 0.71 | PIM1 (0.31) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5633886 | 0.70 | PIM1 (0.31) | — | |
| SCHEMBL5695252 | 0.68 | ADRA2A (0.44) | LCKEGFRSRCZAP70ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664058-B1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-11-14 | — | — | EP | disclosed |
| EP-1664058-B1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-11-14 | — | — | EP | disclosed |
| US-7179830-B2 | Substituted thienoimidazoles useful for disease treatment and prevention | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-02-20 | — | — | US | disclosed |
| US-7179830-B2 | Substituted thienoimidazoles useful for disease treatment and prevention | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-02-20 | — | — | US | disclosed |
| EP-1664058-A1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | Sanofi-Aventis Deutschland GmbH (DE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026173-A1 | SUBSTITUTED THIENOIMIDAZOLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENTS COMPRISING THE SAME | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-03-24 | — | — | WO | disclosed |