SCHEMBL523704

SCHEMBL523704

CSc1cc[c]cc1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6689007 0.83
SCHEMBL456572 0.80
SCHEMBL1355970 0.74
SCHEMBL457212 0.74
SCHEMBL443199 0.74
SCHEMBL161769 0.74
SCHEMBL7473611 0.74 SMN1; SMN2 (0.30)
SCHEMBL58209 0.73
SCHEMBL11148751 0.73 L3MBTL1 (0.36)
SCHEMBL7276412 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041212-A Preparation and application of difluoro olefin ether and oxime ether derivatives 安徽农业大学 2023-05-02 CN claimed
US-9321729-B2 Substituted pyridyl amide compounds as modulators of the histamine H3 receptor JANSSEN PHARMACEUTICA NV (BE) 2016-04-26 US claimed
EP-2032536-B1 SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR JANSSEN PHARMACEUTICA NV (BE) 2015-05-06 EP claimed
US-20150087635-A1 SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR JANSSEN PHARMACEUTICA NV (BE) 2015-03-26 US claimed
US-20140107105-A1 SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR JANSSEN PHARMACEUTICA NV (US) 2014-04-17 US claimed
US-20100267701-A1 SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR JANSSEN PHARMACEUTICA NV (BE) 2010-10-21 US claimed
WO-2010103429-A1 1,1-(Dimethyl-Ethylamino)-2-Hydroxy-Propoxy]-Ethyl}-3-Methyl-Biphenyl-4- Carboxylic Acid Derivatives As Calcium Receptor Antagonists PFIZER INC. (US) 2010-09-16 WO claimed
US-7767666-B2 Butyl and butynyl benzyl amine compounds JANSSEN PHARMACEUTICA NV (BE) 2010-08-03 US claimed
US-20090137562-A1 SUBSTITUTED BENZYL AMINE COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2009-05-28 US claimed
EP-2049473-A2 SUBSTITUTED BENZYL AMINE COMPOUNDS JANSSEN PHARMACEUTICA N.V. (BE) 2009-04-22 EP claimed
WO-2007143422-A2 SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR JANSSEN PHARMACEUTICA N.V. (BE) 2007-12-13 WO claimed
US-20070281923-A1 SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR JANSSEN PHARMACEUTICA N.V. (BE) 2007-12-06 US claimed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
EP-0479834-A4 MONOCLONAL AND POLYCLONAL ANTIBODIES AND TEST METHOD FOR DETERMINATION OF FENITROTHION AND CLOSELY RELATED ORGANOPHOSPHATES 1992-09-30 EP claimed
EP-0289909-B1 ALL AQUEOUS FORMULATIONS OF ORGANO-PHOSPHOROUS PESTICIDES BASF Corporation (US) 1992-09-16 EP claimed
EP-0479834-A1 MONOCLONAL AND POLYCLONAL ANTIBODIES AND TEST METHOD FOR DETERMINATION OF FENITROTHION AND CLOSELY RELATED ORGANOPHOSPHATES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1992-04-15 EP claimed
WO-1991000294-A1 MONOCLONAL AND POLYCLONAL ANTIBODIES AND TEST METHOD FOR DETERMINATION OF FENITROTHION AND CLOSELY RELATED ORGANOPHOSPHATES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1991-01-10 WO claimed
US-4965256-A ENHANCED DURATION OF ACTIVITY BAYER AKTIENGESELLSCHAFT (DE) 1990-10-23 US claimed
US-4965254-A Soil insecticide, miticide BAYER AKTIENGESELLSCHAFT (DE) 1990-10-23 US claimed
US-3966921-A NEMATOCIDES CIBA-GEIGY CORPORATION (US) 1976-06-29 US claimed