Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL28473316 | 0.94 | TSHR (0.57) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL254882 | 0.93 | TSHR (0.59) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29657201 | 0.87 | ALDH1A1 (0.59) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL254364 | 0.87 | ALDH1A1 (0.59) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| Benzene SCHEMBL28132022 | 0.87 | ALDH1A1 (0.59) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| Hydrogen Peroxide SCHEMBL9514730 | 0.87 | ALDH1A1 (0.59) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28432760 | 0.85 | ALDH1A1 (0.56) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL11877644 | 0.85 | ALDH1A1 (0.56) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4068453 | 0.84 | TSHR (0.50) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| Hydrazine SCHEMBL27571459 | 0.83 | ALDH1A1 (0.54) | LMNAKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765796-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | Pfizer Products Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006003495-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2006-01-12 | — | — | WO | disclosed |