Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441088 | 0.93 | KDM4E (0.62) | KDM4EMAPK1HIF1AALDH1A1L3MBTL1 | |
| SCHEMBL7445070 | 0.91 | KDM4E (0.67) | KDM4EMAPK1HIF1AALDH1A1L3MBTL1 | |
| SCHEMBL9491670 | 0.91 | KDM4E (0.67) | KDM4EMAPK1HIF1AALDH1A1L3MBTL1 | |
| SCHEMBL29315300 | 0.91 | KDM4E (0.67) | KDM4EMAPK1HIF1AALDH1A1L3MBTL1 | |
| SCHEMBL16312310 | 0.86 | ALDH1A1 (0.54) | KDM4EMAPK1HIF1AALDH1A1FAAH | |
| SCHEMBL279485 | 0.86 | MAPK1 (0.50) | KDM4EMAPK1HIF1AALDH1A1PAOX | |
| SCHEMBL17578778 | 0.84 | ALDH1A1 (0.52) | KDM4EMAPK1HIF1AALDH1A1FAAH | |
| SCHEMBL17578616 | 0.83 | TSHR (0.57) | KDM4EALDH1A1FAAHACHETSHR | |
| SCHEMBL67905 | 0.81 | ALDH1A1 (0.58) | ALDH1A1PAOXFAAHACHETSHR | |
| SCHEMBL18412265 | 0.81 | ATM (0.55) | KDM4EMAPK1HIF1AL3MBTL1PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| EP-1380121-B1 | PROCESS TO PREPARE OXAZOLIDINONES | PHARMACIA & UPJOHN CO LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| US-7087784-B2 | Process to prepare oxazolidinones | PHARMACIA & UPJOHN (US) | 2006-08-08 | — | — | US | disclosed |
| US-6887995-B2 | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 2005-05-03 | — | — | US | disclosed |
| US-20040220407-A1 | Process to prepare oxazolidinones | PERRAULT WILLIAM R | 2004-11-04 | — | — | US | disclosed |
| EP-1380121-A2 | PROCESS TO PREPARE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| US-20020169312-A1 | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY | 2002-11-14 | — | — | US | disclosed |
| WO-2002085849-A2 | PROCESS TO PREPARE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220407-A1 | Process to prepare oxazolidinones | CYP3A5, OXA1L, CYP3A4 | KDM4E 1853/4885MAPK1 1862/4885HIF1A 1792/4885 |
| US-20020169312-A1 | Process to prepare oxazolidinones | CYP3A5, OXA1L, CYP3A4 | KDM4E 1853/4885MAPK1 1862/4885HIF1A 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.