Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 2/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29911166 | 1.00 | RECQL (0.53) | RECQLFADS1NOS2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30522383 | 0.98 | RECQL (0.51) | RECQLFADS1NOS2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16992931 | 0.98 | RECQL (0.51) | RECQLFADS1NOS2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30522385 | 0.96 | RECQL (0.50) | RECQLFADS1NOS2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1052365 | 0.96 | RECQL (0.50) | RECQLFADS1NOS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8087168 | 0.87 | RECQL (0.56) | RECQLFADS1NOS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL25261672 | 0.83 | RECQL (0.54) | RECQLFADS1NOS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13151996 | 0.81 | RECQL (0.53) | RECQLFADS1NOS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9937692 | 0.81 | ALDH1A1 (0.59) | RECQLALDH1A1SMN1; SMN2CYP3A4TSHR | |
| SCHEMBL121698 | 0.81 | TMPRSS4 (0.44) | ALDH1A1SMN1; SMN2TSHRKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979877-A | Refining method for improving purity of 4-chloro-2-trifluoroacetylaniline mother liquor | 盐城迪赛诺制药有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-108947855-B | Synthesis method of efavirenz key intermediate | 江苏沙星化工有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-109761829-A | A kind of preparation method of high chiral purity efavirenz intermediate | 盐城迪赛诺制药有限公司 | 2019-05-17 | — | — | CN | claimed |
| US-9156756-B2 | Efficient process to induce enantioselectivity in procarbonyl compounds | LAURUS LABS PRIVATE LIMITED (IN) | 2015-10-13 | — | — | US | claimed |
| CN-110776406-B | Novel Friedel-Crafts reaction method and catalyst thereof | 福建永晶科技股份有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115073310-A | Method for reducing specific impurities in efavirenz key intermediate mother liquor | 盐城迪赛诺制药有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-114989023-A | Refining method for improving purity of efavirenz key intermediate mother liquor | 盐城迪赛诺制药有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-113880693-B | Method for recovering trifluoroethanol in multi-component solvent | 盐城迪赛诺制药有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-114920268-A | Method for separating metal salts from mixed salts in efavirenz intermediate production wastewater | 盐城迪赛诺制药有限公司 | 2022-08-19 | — | — | CN | disclosed |
| WO-2022061920-A1 | METHOD FOR PREPARING 3',5'-DICHLORO-2,2,2-TRIFLUOROACETOPHENONE | 台州臻挚生物科技有限公司 | 2022-03-31 | — | — | WO | disclosed |
| CN-113979877-A | Refining method for improving purity of 4-chloro-2-trifluoroacetylaniline mother liquor | 盐城迪赛诺制药有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113979877-A | Refining method for improving purity of 4-chloro-2-trifluoroacetylaniline mother liquor | 盐城迪赛诺制药有限公司 | 2022-01-28 | — | — | CN | disclosed |
| WO-1998027034-A1 | AN IMPROVED SYNTHESIS OF CYCLOPROPYLACETYLENE | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |
| WO-1998014436-A1 | 4,4-DISUBSTITUTED-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONES USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS AND INTERMEDIATES AND PROCESSES FOR MAKING THE SAME | DUPONT PHARMACEUTICALS COMPANY (US) | 1998-04-09 | — | — | WO | disclosed |
| US-5665720-A | MIXTURE WITH NUCLEOSIDE ANALOG | MERCK & CO., INC. (US) | 1997-09-09 | — | — | US | disclosed |
| US-5663169-A | Benzoxazinones as inhibitors of HIV reverse transcriptase | MERCK & CO., INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5519021-A | Benzoxazinones as inhibitors of HIV reverse transcriptase | MERCK & CO., INC. (US) | 1996-05-21 | — | — | US | disclosed |
| WO-1995020389-A1 | BENZOXAZINONES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1995-08-03 | — | — | WO | disclosed |
| WO-1994003440-A1 | BENZOXAZINONES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| EP-0582455-A1 | Benzoxazinones as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1994-02-09 | — | — | EP | disclosed |