Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236086 | 0.85 | CDK8 (0.46) | CDK8CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5236079 | 0.85 | CDK8 (0.46) | CDK8CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5234409 | 0.79 | AKR1C3 (0.50) | CYP2C9CYP2C19ALDH1A1MAPTKMT2A | |
| SCHEMBL5234723 | 0.79 | AOC3 (0.42) | CDK8CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5234707 | 0.79 | AOC3 (0.42) | CDK8CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5234715 | 0.79 | AOC3 (0.42) | CDK8CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21750394 | 0.77 | MAPT (0.56) | CYP2C19ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL21756262 | 0.75 | CHKA (0.55) | CDK8CYP1A2CYP3A4CYP2D6CSNK1A1 | |
| SCHEMBL5232551 | 0.73 | MAPT (0.53) | CYP2C9CYP2C19ALDH1A1MAPTKMT2A | |
| SCHEMBL5235555 | 0.72 | MAPT (0.47) | ALDH1A1MAPTKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |