Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232551 | 0.94 | MAPT (0.53) | AKR1C3MAPTHTTKDM4EMEN1 | |
| Phenylpiperazine SCHEMBL5667738 | 0.86 | ADRB1 (0.56) | MAPTHTTKDM4EMEN1KMT2A | |
| SCHEMBL5235602 | 0.81 | AKR1C3 (0.44) | AKR1C3MAPTHTTKDM4EMEN1 | |
| SCHEMBL5235613 | 0.81 | AKR1C3 (0.44) | AKR1C3MAPTHTTKDM4EMEN1 | |
| SCHEMBL5230976 | 0.79 | AKR1C3 (0.42) | AKR1C3MAPTHTTKDM4EMEN1 | |
| SCHEMBL5230967 | 0.79 | AKR1C3 (0.42) | AKR1C3MAPTHTTKDM4EMEN1 | |
| SCHEMBL5237445 | 0.79 | CDK8 (0.49) | AKR1C3MAPTHTTMEN1KMT2A | |
| SCHEMBL15707566 | 0.76 | AKR1C3 (0.65) | AKR1C3MAPTMEN1KMT2AUSP2 | |
| SCHEMBL27675667 | 0.76 | MEN1 (0.55) | AKR1C3MAPTMEN1KMT2AUSP2 | |
| SCHEMBL5229423 | 0.74 | PHGDH (0.48) | AKR1C3MAPTHTTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |