Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.61 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860232 | 0.94 | OPRL1 (0.66) | OPRL1OPRM1IDO1MAPTMAPK1 | |
| SCHEMBL4849167 | 0.88 | OPRL1 (0.68) | OPRL1OPRM1IDO1MAPTMAPK1 | |
| SCHEMBL4855464 | 0.87 | OPRL1 (0.66) | OPRL1OPRM1IDO1MAPTMAPK1 | |
| Citric Acid SCHEMBL4858328 | 0.87 | OPRL1 (0.55) | OPRL1OPRM1MAPTMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL4854811 | 0.86 | OPRL1 (0.67) | OPRL1OPRM1IDO1MAPTMAPK1 | |
| SCHEMBL5343485 | 0.85 | OPRL1 (0.74) | OPRL1OPRM1MAPTMAPK1MEN1 | |
| SCHEMBL2379196 | 0.84 | OPRL1 (0.62) | OPRL1OPRM1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5336823 | 0.84 | OPRL1 (0.74) | OPRL1OPRM1MAPTMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL5339275 | 0.84 | OPRL1 (0.60) | OPRL1OPRM1MAPTMEN1KMT2A | |
| SCHEMBL6168849 | 0.84 | OPRL1 (0.59) | OPRL1OPRM1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560809-B1 | CYCLOHEXYLUREA DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-08-22 | — | — | EP | claimed |