Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165082 | 0.99 | OPRL1 (0.58) | OPRL1OPRM1MEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL5339275 | 0.96 | OPRL1 (0.60) | OPRL1OPRM1MEN1KMT2AHPGD | |
| SCHEMBL6159000 | 0.90 | OPRL1 (0.62) | OPRL1OPRM1MTNR1A | |
| SCHEMBL6160062 | 0.89 | OPRL1 (0.49) | OPRL1OPRM1MTNR1A | |
| SCHEMBL6163570 | 0.89 | OPRL1 (0.61) | OPRL1OPRM1MTNR1A | |
| SCHEMBL5340673 | 0.88 | OPRL1 (0.63) | OPRL1OPRM1KMT2ABCHEACHE | |
| SCHEMBL6161294 | 0.87 | OPRL1 (0.63) | OPRL1OPRM1MEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL5336638 | 0.87 | OPRL1 (0.62) | OPRL1OPRM1KMT2ABCHEACHE | |
| SCHEMBL5202013 | 0.87 | OPRL1 (0.61) | OPRL1OPRM1MEN1KMT2AHPGD | |
| SCHEMBL5234590 | 0.86 | OPRL1 (0.60) | OPRL1OPRM1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562891-A1 | 4-AMINOMETHYL-1-ARYL-CYCLOHEXYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004043899-A1 | 4-AMINOMETHYL-1-ARYL-CYCLOHEXYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2004-05-27 | — | — | WO | claimed |
| EP-1562891-A1 | 4-AMINOMETHYL-1-ARYL-CYCLOHEXYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004043899-A1 | 4-AMINOMETHYL-1-ARYL-CYCLOHEXYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2004-05-27 | — | — | WO | disclosed |