Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL354661 | 0.99 | DPP4 (0.53) | DPP4HSD17B10ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL5234491 | 0.91 | DPP4 (0.47) | DPP4ADORA2AADORA2BADORA1PSEN1 | |
| Hydrochloric Acid SCHEMBL5236314 | 0.90 | DPP4 (0.44) | DPP4ALDH1A1PSEN1PSEN2APH1B | |
| Hydrochloric Acid SCHEMBL5235033 | 0.90 | DPP4 (0.44) | DPP4KDM4EMAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5234616 | 0.88 | DPP4 (0.43) | DPP4HSD17B10ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL5239297 | 0.88 | DPP4 (0.43) | DPP4HSD17B10ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL5239042 | 0.86 | DPP4 (0.69) | DPP4 | |
| SCHEMBL5237142 | 0.86 | DPP4 (0.41) | DPP4KDM4ELMNAMAPK1 | |
| SCHEMBL7005880 | 0.86 | DPP4 (0.41) | DPP4ALDH1A1KDM4EPSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL5234677 | 0.86 | DPP4 (0.46) | DPP4HSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2007-07-11 | — | — | EP | disclosed |