Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | HTR1D | P28221 | 3/20 | 0.32 |
| ▸ | HTR1B | P28222 | 3/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5239225 | 0.99 | DPP4 (0.41) | DPP4PGRRORARORCRORB | |
| Hydrochloric Acid SCHEMBL5235033 | 0.94 | DPP4 (0.44) | DPP4PGRRORARORCRORB | |
| Hydrochloric Acid SCHEMBL5239297 | 0.92 | DPP4 (0.43) | DPP4PGRRORARORCRORB | |
| Hydrochloric Acid SCHEMBL5234677 | 0.90 | DPP4 (0.46) | DPP4PGRRORARORCRORB | |
| Hydrochloric Acid SCHEMBL5234616 | 0.90 | DPP4 (0.43) | DPP4PGRRORARORCRORB | |
| Hydrochloric Acid SCHEMBL5238860 | 0.89 | DPP4 (0.42) | DPP4PGRALDH1A1HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL5232098 | 0.88 | DPP4 (0.41) | DPP4PGRALDH1A1HTR1AHTR1D | |
| SCHEMBL5237492 | 0.87 | DPP4 (0.42) | DPP4ALDH1A1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5238316 | 0.86 | DPP4 (0.40) | DPP4PGRRORARORCRORB | |
| Hydrochloric Acid SCHEMBL5231311 | 0.86 | DPP4 (0.43) | DPP4ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062764-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-15 | — | — | WO | disclosed |