Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239135 | 1.00 | HPGD (0.39) | HPGDALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL5239138 | 1.00 | HPGD (0.39) | HPGDALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL11604586 | 0.79 | ALDH1A1 (0.36) | HPGDALDH1A1MAPT | |
| SCHEMBL11604584 | 0.79 | ALDH1A1 (0.36) | HPGDALDH1A1MAPT | |
| SCHEMBL1038685 | 0.77 | HPGD (0.46) | HPGDALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL1492015 | 0.77 | HPGD (0.46) | HPGDALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL5239873 | 0.77 | MAPT (0.34) | HPGDALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL5239882 | 0.77 | MAPT (0.34) | HPGDALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL5239879 | 0.77 | MAPT (0.34) | HPGDALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL3865443 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | SANKYO COMPANY, LIMITED (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | RASGRP1, NRAS, HRH3 | HPGD 2215/4885ALDH1A1 1073/4885L3MBTL1 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.