Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4156720 | 0.99 | MAPT (0.57) | MAPTNPSR1POLBPKMMEN1 | |
| Hydrochloric Acid SCHEMBL4162672 | 0.99 | MAPT (0.57) | MAPTNPSR1POLBPKMMEN1 | |
| Bromide SCHEMBL4171632 | 0.99 | MAPT (0.57) | MAPTNPSR1POLBPKMMEN1 | |
| Hydrochloric Acid SCHEMBL4154088 | 0.94 | NPSR1 (0.59) | MAPTNPSR1POLBPKMMEN1 | |
| Bromide SCHEMBL4167080 | 0.94 | NPSR1 (0.59) | MAPTNPSR1POLBPKMMEN1 | |
| Iodide SCHEMBL4155323 | 0.94 | NPSR1 (0.59) | MAPTNPSR1POLBPKMMEN1 | |
| Bromide SCHEMBL4149889 | 0.88 | MAPT (0.57) | MAPTNPSR1POLBPKMMEN1 | |
| Iodide SCHEMBL4157647 | 0.88 | MAPT (0.57) | MAPTNPSR1POLBPKMMEN1 | |
| Iodide SCHEMBL4155340 | 0.87 | ALDH1A1 (0.61) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| Iodide SCHEMBL4164756 | 0.85 | MAPT (0.60) | MAPTNPSR1POLBPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798227-A1 | SEROTONIN 5-HT3 RECEPTOR AGONIST | Research Foundation Itsuu Laboratory (JP) | 2007-06-20 | — | — | EP | disclosed |