SCHEMBL5239666

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5477771	0.89	KDR (1.00)	KDRFLT1HDAC3HDAC4HDAC1
	SCHEMBL22630824	0.89	KDR (0.69)	KDREGFRRETAURKAERBB2
	SCHEMBL14964683	0.89	EGFR (0.80)	KDRHDAC3HDAC4HDAC1HDAC7
	SCHEMBL6688859	0.89	KDR (0.67)	KDRFLT1EGFRRETGAK
	SCHEMBL5240218	0.89	EGFR (0.79)	KDRFLT1EGFRRETGAK
	SCHEMBL30968994	0.89	EGFR (0.82)	KDRHDAC3HDAC4HDAC1HDAC7
	SCHEMBL3328655	0.89	EGFR (0.82)	KDRHDAC3HDAC4HDAC1HDAC7
	Hydrochloric Acid SCHEMBL5473772	0.88	KDR (0.97)	KDRFLT1HDAC3HDAC4HDAC1
	Hydrochloric Acid SCHEMBL641764	0.88	EGFR (0.80)	KDRHDAC3HDAC4HDAC1HDAC7
	SCHEMBL31067633	0.88	KDR (0.82)	KDRFLT1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.