Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.67 |
| ▸ | EGFR | P00533 | 7/20 | 0.67 |
| ▸ | GAK | O14976 | 1/20 | 0.65 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.65 |
| ▸ | STK10 | O94804 | 1/20 | 0.65 |
| ▸ | RET | P07949 | 1/20 | 0.65 |
| ▸ | FLT3 | P36888 | 1/20 | 0.65 |
| ▸ | JAK3 | P52333 | 1/20 | 0.65 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.65 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.65 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.65 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.65 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.65 |
| ▸ | LCK | P06239 | 3/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.64 |
| ▸ | FLT1 | P17948 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473733 | 0.94 | KDR (0.74) | KDREGFRGAKRIPK2STK10 | |
| Hydrochloric Acid SCHEMBL5477767 | 0.93 | EGFR (0.73) | KDREGFRGAKRIPK2STK10 | |
| SCHEMBL14964683 | 0.89 | EGFR (0.80) | KDREGFRGAKRIPK2STK10 | |
| SCHEMBL5239666 | 0.89 | KDR (0.80) | KDREGFRGAKRIPK2STK10 | |
| SCHEMBL5240218 | 0.89 | EGFR (0.79) | KDREGFRGAKRIPK2STK10 | |
| SCHEMBL3238919 | 0.88 | EGFR (0.70) | KDREGFRGAKRETLCK | |
| SCHEMBL6689820 | 0.87 | AURKB (0.73) | KDREGFRGAKRIPK2STK10 | |
| Hydrochloric Acid SCHEMBL3238911 | 0.87 | EGFR (0.68) | KDREGFRGAKRETLCK | |
| SCHEMBL6689899 | 0.86 | AURKB (0.69) | KDREGFRGAKRIPK2STK10 | |
| SCHEMBL6691540 | 0.85 | KDR (0.66) | KDREGFRIRAK4AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |