Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977162 | 0.88 | ACACB (0.33) | ACACBALDH1A1 | |
| SCHEMBL6184495 | 0.83 | ACACB (0.32) | ACACBCYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL5236773 | 0.82 | ACACB (0.39) | ACACBCYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL13976844 | 0.81 | ALDH1A1 (0.32) | ACACBALDH1A1 | |
| SCHEMBL13860726 | 0.81 | ALDH1A1 (0.32) | ACACBALDH1A1 | |
| SCHEMBL28758678 | 0.79 | ACACB (0.33) | ACACB | |
| SCHEMBL27553731 | 0.79 | ACACB (0.34) | ACACBALDH1A1 | |
| SCHEMBL3834654 | 0.76 | ACACB (0.35) | ACACBALDH1A1 | |
| SCHEMBL6183397 | 0.76 | ACACB (0.34) | ACACB | |
| SCHEMBL5709213 | 0.76 | ACACB (0.34) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819686-A1 | 5-HYDROXY-BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECPTOR AGONIST ACTIVITY | Novartis AG (CH) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056471-A1 | 5-HYDROXY-BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECPTOR AGONIST ACTIVITY | NOVARTIS AG (CH) | 2006-06-01 | — | — | WO | disclosed |