Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5454619 | 0.90 | DPP4 (0.67) | DPP4DPP9DPP8 | |
| SCHEMBL5242334 | 0.89 | DPP4 (0.48) | DPP4DPP9DPP8 | |
| SCHEMBL4113165 | 0.86 | DPP4 (0.56) | DPP4DPP9DPP8 | |
| SCHEMBL5240229 | 0.84 | DPP4 (0.43) | DPP4DPP9DPP8KDM4EALDH1A1 | |
| SCHEMBL5241485 | 0.83 | DPP4 (0.53) | DPP4DPP9DPP8 | |
| SCHEMBL5739328 | 0.82 | DPP4 (0.59) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL27664813 | 0.82 | DPP4 (0.56) | DPP4DPP9DPP8 | |
| SCHEMBL5242122 | 0.81 | DPP4 (0.49) | DPP4DPP9DPP8KDM4EALDH1A1 | |
| SCHEMBL5740898 | 0.77 | DPP4 (0.69) | DPP4DPP9DPP8ALDH1A1 | |
| SCHEMBL5741240 | 0.77 | DPP4 (0.45) | DPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851202-A1 | PYRIDYL ACETIC ACID COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006090915-A1 | PYRIDYL ACETIC ACID COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-08-31 | — | — | WO | disclosed |
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |