Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.69 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5449372 | 0.92 | DPP4 (0.83) | DPP4DPP9DPP8 | |
| SCHEMBL5442960 | 0.90 | DPP4 (0.66) | DPP4DPP9DPP8 | |
| SCHEMBL5740897 | 0.85 | DPP4 (0.57) | DPP4DPP9DPP8ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL27643586 | 0.83 | DPP4 (0.71) | DPP4DPP9DPP8 | |
| SCHEMBL5739328 | 0.83 | DPP4 (0.59) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL5448610 | 0.78 | DPP4 (0.66) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL5469864 | 0.78 | DPP4 (0.80) | DPP4DPP9DPP8 | |
| SCHEMBL5740457 | 0.78 | DPP4 (0.53) | DPP4DPP9DPP8 | |
| SCHEMBL5240233 | 0.77 | DPP4 (0.53) | DPP4DPP9DPP8ALDH1A1 | |
| SCHEMBL5449916 | 0.77 | DPP4 (0.53) | DPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |