Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | GGT1 | P19440 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477006 | 0.81 | ALDH1A1 (0.59) | KDM4EKMT2AMEN1RECQLABCB1 | |
| SCHEMBL10821861 | 0.81 | KDM4E (0.52) | KDM4EKMT2AMEN1RECQLABCB1 | |
| SCHEMBL11629879 | 0.80 | ABCB1 (0.53) | ABCB1HTTLMNATSHR | |
| SCHEMBL1552388 | 0.80 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLABCB1 | |
| Benzene SCHEMBL28043964 | 0.80 | ALDH1A1 (0.57) | KDM4EKMT2AMEN1RECQLABCB1 | |
| Bicarbonate SCHEMBL20694841 | 0.80 | ALDH1A1 (0.57) | KDM4EKMT2AMEN1RECQLABCB1 | |
| Bicarbonate SCHEMBL29943829 | 0.80 | ALDH1A1 (0.57) | KDM4EKMT2AMEN1RECQLABCB1 | |
| SCHEMBL17799583 | 0.80 | ALDH1A1 (0.57) | KDM4EKMT2AMEN1RECQLABCB1 | |
| Bicarbonate SCHEMBL236893 | 0.80 | ALDH1A1 (0.57) | KDM4EKMT2AMEN1RECQLABCB1 | |
| SCHEMBL9627874 | 0.79 | ABCB1 (0.65) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598472-A2 | FORMULATIONS | Syngenta Limited (GB) | 2013-06-05 | — | — | EP | claimed |
| WO-2012014152-A2 | FORMULATIONS | SYNGENTA LIMITED (GB) | 2012-02-02 | — | — | WO | claimed |