Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 20/20 | 0.69 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233542 | 0.94 | TGFBR1 (0.68) | TGFBR1THRBMAPK14 | |
| SCHEMBL5231734 | 0.92 | TGFBR1 (0.67) | TGFBR1 | |
| SCHEMBL5236049 | 0.92 | TGFBR1 (0.67) | TGFBR1THRBMAPK14 | |
| SCHEMBL5236693 | 0.92 | TGFBR1 (0.69) | TGFBR1 | |
| SCHEMBL5240971 | 0.91 | TGFBR1 (0.69) | TGFBR1 | |
| SCHEMBL5240902 | 0.91 | TGFBR1 (0.69) | TGFBR1 | |
| SCHEMBL5238797 | 0.91 | TGFBR1 (0.64) | TGFBR1THRBMAPK14 | |
| SCHEMBL5239961 | 0.91 | TGFBR1 (0.64) | TGFBR1THRBMAPK14 | |
| SCHEMBL5234991 | 0.91 | TGFBR1 (0.68) | TGFBR1THRBMAPK14 | |
| SCHEMBL5237019 | 0.90 | TGFBR1 (0.73) | TGFBR1THRBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397364-B1 | NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | LILLY CO ELI (US) | 2007-07-25 | — | — | EP | claimed |