SCHEMBL52407

SCHEMBL52407

N=C(OCc1ccccc1)C(Cl)(Cl)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
TDP1 Q9NUW8 2/20 0.46
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 1/20 0.46
TSHR P16473 1/20 0.43
LMNA P02545 2/20 0.42
HCAR2 Q8TDS4 1/20 0.42
OPRK1 P41145 1/20 0.40
IDO1 P14902 1/20 0.40
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP12 P39900 1/20 0.39
AGXT P21549 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28175162 0.90 ALDH1A1 (0.51) ALDH1A1CA12CA1CA2CA9
SCHEMBL1968907 0.89 IDO1 (0.47) ALDH1A1CA12CA1CA2CA9
SCHEMBL31750770 0.88 CYP1A2 (0.54) L3MBTL1SLC6A2SLC6A3KMT2ALMNA
SCHEMBL24790474 0.85 ALDH1A1 (0.48) ALDH1A1CA12CA1CA2CA9
SCHEMBL13180669 0.84 MEN1 (0.46) ALDH1A1CA2L3MBTL1SLC6A2KMT2A
SCHEMBL29592808 0.83 ALDH1A1 (0.49) ALDH1A1LMNAOPRK1
SCHEMBL12387355 0.82 PRSS1 (0.39) ALDH1A1CA12CA1CA2CA9
SCHEMBL2221024 0.81 IDO1 (0.44) ALDH1A1KMT2AIDO1
SCHEMBL4963068 0.81 IDO1 (0.44) L3MBTL1KMT2ALMNAOPRK1IDO1
SCHEMBL6260611 0.81 ALDH1A1 (0.40) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 881 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708838-B2 Chemical sequestration of wellbore fluids in electric submersible pump systems HALLIBURTON ENERGY SERVICES, INC. (US) 2023-07-25 US claimed
EP-3634970-B1 NOVEL PROCESS FOR PREPARATION OF EMPAGLIFLOZIN OR ITS CO-CRYSTALS, SOLVATES AND THEIR POLYMORPHS THEREOF LAURUS LABS LTD (IN) 2023-07-19 EP claimed
US-20220003240-A1 CHEMICAL SEQUESTRATION OF WELLBORE FLUIDS IN ELECTRIC SUBMERSIBLE PUMP SYSTEMS HALLIBURTON ENERGY SERVICES, INC. 2022-01-06 US claimed
WO-2022005484-A1 CHEMICAL SEQUESTRATION OF WELLBORE FLUIDS IN ELECTRIC SUBMERSIBLE PUMP SYSTEMS HALLIBURTON ENERGY SERVICES, INC. (US) 2022-01-06 WO claimed
US-11046676-B2 Process for preparation of empagliflozin or its co-crystals, solvates and their polymorphs thereof LAURUS LABS LIMITED (IN) 2021-06-29 US claimed
US-20200131163-A1 NOVEL PROCESS FOR PREPARATION OF EMPAGLIFLOZIN OR ITS CO-CRYSTALS, SOLVATES AND THEIR POLYMORPHS THEREOF LAURUS LABS LIMITED (IN) 2020-04-30 US claimed
EP-3634970-A1 NOVEL PROCESS FOR PREPARATION OF EMPAGLIFLOZIN OR ITS CO-CRYSTALS, SOLVATES AND THEIR POLYMORPHS THEREOF Laurus Labs Limited (IN) 2020-04-15 EP claimed
WO-2018224957-A1 NOVEL PROCESS FOR PREPARATION OF EMPAGLIFLOZIN OR ITS CO-CRYSTALS, SOLVATES AND THEIR POLYMORPHS THEREOF LAURUS LABS LIMITED (IN) 2018-12-13 WO claimed
CN-105272852-A Ezetimibe intermediate and preparation method ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO LTD 2016-01-27 CN claimed
US-20150177238-A1 PROCESS FOR THE MANUFACTURING OF GLYCOCHIPS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-06-25 US claimed
WO-2008059307-A2 FUNCTIONALIZED BETA 1,6 GLUCOSAMINE DISACCHARIDES AND PROCESS FOR THEIR PREPARATION OM PHARMA (CH) 2008-05-22 WO claimed
WO-2008059035-A2 FUNCTIONALIZED BETA 1,6 GLUCOSAMINE DISACCHARIDES AND PROCESS FOR THEIR PREPARATION OM PHARMA (CH) 2008-05-22 WO claimed
US-7160517-B2 Apparatus and methods for the automated synthesis of oligosaccharides MASSACHUSETTS INSTITUTE OF TECHNOLGY (US) 2007-01-09 US claimed
EP-1315559-B1 APPARATUS AND METHODS FOR THE AUTOMATED SYNTHESIS OF OLIGOSACCHARIDES MASSACHUSETTS INST TECHNOLOGY (US) 2006-03-22 EP claimed
EP-1315559-A2 APPARATUS AND METHODS FOR THE AUTOMATED SYNTHESIS OF OLIGOSACCHARIDES Massachusetts Institute Of Technology (US) 2003-06-04 EP claimed
US-20020085964-A1 Apparatus and methods for the automated synthesis of oligosaccharides MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2002-07-04 US claimed
WO-2002016384-A2 APPARATUS AND METHODS FOR THE AUTOMATED SYNTHESIS OF OLIGOSACCHARIDES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-02-28 WO claimed
EP-0660835-A4 PROCESS FOR PREPARING CERTAIN PYRROLO 3,4- -I(B))QUINOLINES, CERTAIN 1H-PYRANO 3',4':6,7)INDOLIZINO 1,2--I(B))QUINOLIN-3,14(4H,12H)-DIONES, AND CERTAIN 8-METHYL-7-(OXOPROPYL)-INDOLIZINO 1,2--I(B))QUINOLIN-9(11H)-ONES. 1995-08-16 EP claimed
EP-0660835-A1 PROCESS FOR PREPARING CERTAIN PYRROLO 3,4- $i(b)]QUINOLINES, CERTAIN 1H-PYRANO 3',4':6,7]INDOLIZINO 1,2-$i(b)]QUINOLIN-3,14(4H,12H)-DIONES, AND CERTAIN 8-METHYL-7-(OXOPROPYL)-INDOLIZINO 1,2-$i(b)]QUINOLIN-9(11H)-ONES SMITHKLINE BEECHAM CORPORATION (US) 1995-07-05 EP claimed
WO-1994005672-A1 PROCESS FOR PREPARING CERTAIN PYRROLO[3,4- b]QUINOLINES, CERTAIN 1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-b]QUINOLIN-3,14(4H,12H)-DIONES, AND CERTAIN 8-METHYL-7-(OXOPROPYL)-INDOLIZINO[1,2-b]QUINOLIN-9(11H)-ONES SMITHKLINE BEECHAM CORPORATION (US) 1994-03-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131163-A1 NOVEL PROCESS FOR PREPARATION OF EMPAGLIFLOZIN OR ITS CO-CRYSTALS, SOLVATES AND THEIR POLYMORPHS THEREOF SLC5A1, SLC5A2, DPP4 ALDH1A1 2860/4885CA12 2194/4885CA1 3525/4885
US-11046676-B2 Process for preparation of empagliflozin or its co-crystals, solvates and their polymorphs thereof SLC5A2, SLC5A1, DPP4 ALDH1A1 2460/4885CA12 1643/4885CA1 3045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.