Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.43 |
| ▸ | MMP14 | P50281 | 9/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289321 | 1.00 | MMP13 (0.43) | MMP13MMP14MMP12 | |
| SCHEMBL5237716 | 0.91 | MMP13 (0.44) | MMP13MMP14MMP12 | |
| SCHEMBL4781756 | 0.91 | MMP13 (0.44) | MMP13MMP14MMP12 | |
| SCHEMBL2289892 | 0.91 | MMP13 (0.44) | MMP13MMP14MMP12 | |
| SCHEMBL2287069 | 0.91 | MMP13 (0.44) | MMP13MMP14MMP12 | |
| SCHEMBL2287435 | 0.90 | MMP13 (0.42) | MMP13MMP14MMP12 | |
| SCHEMBL3647385 | 0.90 | MMP13 (0.42) | MMP13MMP14MMP12 | |
| SCHEMBL2293088 | 0.89 | MMP13 (0.46) | MMP13MMP14MMP12 | |
| SCHEMBL5241162 | 0.89 | MMP13 (0.46) | MMP13MMP14MMP12 | |
| SCHEMBL2287095 | 0.89 | MMP13 (0.44) | MMP13MMP14MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778673-A1 | NOVEL HYDANTOIN DERIVATIVES FOR THE TREATMENT OF OBSTRUCTIVE AIRWAY DISEASES | AstraZeneca AB (SE) | 2007-05-02 | — | — | EP | claimed |
| WO-2006004532-A1 | NOVEL HYDANTOIN DERIVATIVES FOR THE TREATMENT OF OBSTRUCTIVE AIRWAY DISEASES | ASTRAZENECA AB (SE) | 2006-01-12 | — | — | WO | claimed |