⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24630408 | 1.00 | — | — | |
| SCHEMBL524141 | 1.00 | — | — | |
| SCHEMBL16429781 | 0.82 | — | — | |
| SCHEMBL523257 | 0.82 | — | — | |
| SCHEMBL3000480 | 0.82 | — | — | |
| SCHEMBL28929502 | 0.77 | — | — | |
| SCHEMBL524454 | 0.77 | — | — | |
| SCHEMBL6921399 | 0.77 | — | — | |
| SCHEMBL17342284 | 0.77 | — | — | |
| SCHEMBL9614688 | 0.77 | HLCS (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132811-B1 | 1-SUBSTITUTED 4-HYDROXYMETHYL-PYRROLIDINONES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND INTERMEDIATE | BOEHRINGER INGELHEIM KG (DE) | 1988-09-28 | — | — | EP | claimed |
| EP-0132811-A1 | 1-Substituted 4-hydroxymethyl-pyrrolidinones, processes for their preparation, pharmaceutical composition and intermediate | BOEHRINGER INGELHEIM KG (DE) | 1985-02-13 | — | — | EP | claimed |
| US-4144245-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1979-03-13 | — | — | US | claimed |
| US-4119637-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1978-10-10 | — | — | US | claimed |
| WO-2026107328-A1 | AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS | SEPTERNA, INC. (US) | 2026-05-21 | — | — | WO | disclosed |
| US-12624028-B2 | 1H-pyrazolo[4,3-G]isoquinoline and 1H-pyrazolo[4,3-g]quinoline derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (AATD) | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2026-05-12 | — | — | US | disclosed |
| US-12559506-B2 | Indazole based compounds and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-12545684-B2 | CDK2 inhibitors | BLUEPRINT MEDICINES CORPORATION (US) | 2026-02-10 | — | — | US | disclosed |
| EP-4436667-B1 | PIPERAZINYLSULFONYLARYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | HOFFMANN LA ROCHE (CH) | 2026-01-21 | — | — | EP | disclosed |
| EP-4680601-A1 | PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES | Sanofi (FR) | 2026-01-21 | — | — | EP | disclosed |
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | SERVIER LAB (FR) | 2026-01-01 | — | — | US | disclosed |
| US-20250353848-A1 | HETEROCYCLIC PAD4 INHIBITORS | CELGENE CORPORATION | 2025-11-20 | — | — | US | disclosed |
| EP-0132811-A1 | 1-Substituted 4-hydroxymethyl-pyrrolidinones, processes for their preparation, pharmaceutical composition and intermediate | BOEHRINGER INGELHEIM KG (DE) | 1985-02-13 | — | — | EP | disclosed |
| US-4144245-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4119637-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4113874-A | PYRROLIDONES, PHARMACEUTICAL COMPOSITIONS THEREWITH AND PROCESSES OF USE THEREOF | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4104284-A | Nitroanthraquinones | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4079145-A | PROSTAGLANDIN ANALOGUES; SPASMOLYTIC, HYPOTENSIVE, ANTISECRETORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |
| US-4071530-A | Pyrrolidones and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-31 | — | — | US | disclosed |
| US-3989450-A | DYEING AND PRINTING SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |