⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20510547 | 0.97 | SHBG (0.43) | — | |
| SCHEMBL5277 | 0.97 | — | — | |
| SCHEMBL6161072 | 0.97 | SHBG (0.43) | — | |
| SCHEMBL4228253 | 0.97 | SHBG (0.43) | — | |
| SCHEMBL4326 | 0.97 | SHBG (0.43) | — | |
| SCHEMBL23628575 | 0.97 | — | — | |
| SCHEMBL5144 | 0.97 | SHBG (0.43) | — | |
| SCHEMBL5482 | 0.93 | — | — | |
| SCHEMBL22534005 | 0.86 | — | — | |
| SCHEMBL5173 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 676 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459043-B | Naphthyridines derovatives | 诺华股份有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-106459043-A | Naphthyridinedione derivatives | 诺华股份有限公司 | 2017-02-22 | — | — | CN | claimed |
| US-7279527-B2 | Method of converting anionic living end to protected free radical living end and applications thereof | BRIDGESTONE CORPORATION (JP) | 2007-10-09 | — | — | US | claimed |
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-01 | — | — | US | claimed |
| US-20060241265-A1 | Method of converting anionic living end to protected free radical living end and applications thereof | BRIDGESTONE CORPORATION (JP) | 2006-10-26 | — | — | US | claimed |
| EP-0903357-B1 | Synthesis of 1,4-trans-polybutadiene using a lanthanide organic acid salt catalyst | BRIDGESTONE CORP (JP) | 2004-01-28 | — | — | EP | claimed |
| EP-1383748-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-01-28 | — | — | EP | claimed |
| WO-2002051983-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-07-04 | — | — | WO | claimed |
| US-6184168-B1 | CATALYST COMPOSITION COMPRISES REACTION PRODUCT OF INGREDIENTS CONSISTING ESSENTIALLY OF AN ORGANOLITHIUM COMPOUND AND AN ORGANIC ACID SALT OF LANTHANIDE SERIES ELEMENT | BRIDGESTONE CORPORATION (JP) | 2001-02-06 | — | — | US | claimed |
| US-6177603-B1 | GELATION INHIBITION AND REDUCTION OF A BROAD MOLECULAR WEIGHT DISTRIBUTION DURING THE HIGH TEMPERATURE HOMOPOLYMERIZATION USING A CATALYST COMPRISING A RARE EARTH SALT, A DIALKYLMAGNESIUM AND AN ORGANOZINC COMPOUND | BRIDGESTONE CORPORATION (JP) | 2001-01-23 | — | — | US | claimed |
| US-5095038-A | Antiinflammatory, antiallergens | ICI AMERICAS INC. (US) | 1992-03-10 | — | — | US | claimed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | claimed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | claimed |
| CN-1037895-A | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICA INC (US) | 1989-12-13 | — | — | CN | claimed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | claimed |
| EP-0337765-A2 | Acylsulfonamide derivatives of alpha-carbocyclyltoluic acids used as leukotriene antagonists | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | claimed |
| EP-0337767-A1 | Cyclic amides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | claimed |
| US-4399147-A | Prostaglandin 12 analogues and their pharmaceutical compositions | ONO PHARMACEUTICAL CO. LTD. (JP) | 1983-08-16 | — | — | US | claimed |
| US-4207332-A | Prostaglandin I2 analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1980-06-10 | — | — | US | claimed |
| US-4178367-A | Prostaglandin I2 analogues | ONO PHARMACEUTICAL CO. LTD. (JP) | 1979-12-11 | — | — | US | claimed |