Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.80 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.80 |
| ▸ | OXTR | P30559 | 6/20 | 0.75 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA7 | P43166 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28801336 | 0.90 | HPGD (0.77) | AVPR2AVPR1AOXTRCA1CA2 | |
| SCHEMBL7347092 | 0.89 | AVPR2 (1.00) | AVPR2AVPR1AOXTRCA1CA2 | |
| SCHEMBL7357300 | 0.87 | AVPR2 (0.97) | AVPR2AVPR1AOXTRCA1CA2 | |
| SCHEMBL5237261 | 0.86 | AVPR2 (0.76) | AVPR2AVPR1AOXTRCA1CA2 | |
| SCHEMBL9389632 | 0.86 | AVPR2 (1.00) | AVPR2AVPR1AOXTRALDH1A1 | |
| SCHEMBL6965406 | 0.84 | AVPR2 (0.92) | AVPR2AVPR1AOXTRCA1CA2 | |
| SCHEMBL7348349 | 0.84 | AVPR2 (0.76) | AVPR2AVPR1AOXTRCA1CA2 | |
| SCHEMBL2937767 | 0.83 | AVPR2 (0.64) | AVPR2AVPR1AOXTR | |
| SCHEMBL29463754 | 0.83 | ALDH1A1 (0.81) | AVPR2AVPR1AOXTRCA1CA2 | |
| SCHEMBL6198498 | 0.83 | ALDH1A1 (0.81) | AVPR2AVPR1AOXTRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778677-A1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | Ferring B.V. (NL) | 2007-05-02 | — | — | EP | claimed |
| WO-2006018443-A1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | FERRING B.V. (NL) | 2006-02-23 | — | — | WO | claimed |