Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245851 | 1.00 | PDE5A (0.51) | PDE5AKCNH2 | |
| SCHEMBL5245416 | 0.91 | PDE5A (0.53) | PDE5AKCNH2 | |
| SCHEMBL5246388 | 0.90 | PDE5A (0.53) | PDE5AKCNH2 | |
| SCHEMBL5245526 | 0.90 | PDE5A (0.54) | PDE5AKCNH2 | |
| SCHEMBL5247086 | 0.89 | PDE5A (0.53) | PDE5AKCNH2 | |
| SCHEMBL5244271 | 0.87 | PDE5A (0.55) | PDE5AKCNH2 | |
| SCHEMBL5247381 | 0.86 | PDE5A (0.55) | PDE5AKCNH2 | |
| SCHEMBL5243456 | 0.86 | PDE5A (0.65) | PDE5AKCNH2 | |
| SCHEMBL5245874 | 0.85 | PDE5A (0.69) | PDE5AKCNH2 | |
| SCHEMBL5247249 | 0.85 | PDE5A (0.69) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809632-A2 | PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES USEFUL AS PDE-5 INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006046135-A2 | PYRAZOLO[4,3-D] PYRIMIDINE DERIVATIVES USEFUL AS PDE-5 INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-05-04 | — | — | WO | disclosed |