Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323506 | 0.91 | TSHR (0.47) | TSHRALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL8925139 | 0.85 | TSHR (0.48) | TSHRALDH1A1KMT2AMEN1THRB | |
| SCHEMBL5245072 | 0.84 | CYP2C19 (0.46) | TSHRALDH1A1KMT2AMEN1THRB | |
| SCHEMBL9149193 | 0.84 | TSHR (0.55) | TSHRALDH1A1KMT2AMEN1THRB | |
| SCHEMBL8939139 | 0.83 | TSHR (0.46) | TSHRALDH1A1KMT2AMEN1THRB | |
| SCHEMBL8939120 | 0.83 | TSHR (0.46) | TSHRALDH1A1KMT2AMEN1THRB | |
| SCHEMBL8939107 | 0.83 | TSHR (0.46) | TSHRALDH1A1KMT2AMEN1THRB | |
| SCHEMBL8824119 | 0.83 | TSHR (0.46) | TSHRALDH1A1KMT2AMEN1THRB | |
| SCHEMBL8939127 | 0.83 | TSHR (0.46) | TSHRALDH1A1KMT2AMEN1THRB | |
| SCHEMBL20240559 | 0.82 | ALDH1A1 (0.50) | TSHRALDH1A1KMT2AMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379598-B1 | UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS | BASF AG (DE) | 2007-09-12 | — | — | EP | disclosed |
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |
| EP-1379598-A1 | UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002086000-A1 | UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-31 | — | — | WO | disclosed |