SCHEMBL5246901

SCHEMBL5246901

N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1[O]

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.66
CNR2 P34972 16/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3626666 0.86 CNR1 (0.69) CNR1CNR2
SCHEMBL5246907 0.84 CNR1 (0.66) CNR1CNR2
SCHEMBL3627816 0.81 CNR1 (0.72) CNR1CNR2
SCHEMBL5359404 0.80 CNR1 (1.00) CNR1CNR2
SCHEMBL5360588 0.79 CNR1 (0.61) CNR1CNR2
SCHEMBL5365303 0.79 CNR1 (0.74) CNR1CNR2
SCHEMBL5247158 0.78 CNR1 (0.73) CNR1CNR2
SCHEMBL5363440 0.78 CNR1 (1.00) CNR1CNR2
SCHEMBL5363416 0.78 CNR1 (1.00) CNR1CNR2
SCHEMBL5365312 0.78 CNR1 (0.74) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558252-B1 SUBSTITUTED FURO [2,3-B]PYRIDINE DERIVATIVES MERCK & CO INC (US) 2007-10-10 EP disclosed