Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365303 | 0.89 | CNR1 (0.74) | CNR1CNR2 | |
| SCHEMBL5359368 | 0.86 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL6098948 | 0.85 | CNR1 (0.72) | CNR1CNR2 | |
| SCHEMBL5363952 | 0.85 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL5250920 | 0.84 | CNR1 (0.68) | CNR1CNR2 | |
| SCHEMBL5360353 | 0.84 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL5363017 | 0.84 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL5359404 | 0.83 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL5355026 | 0.83 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL5355779 | 0.83 | CNR1 (1.00) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558252-B1 | SUBSTITUTED FURO [2,3-B]PYRIDINE DERIVATIVES | MERCK & CO INC (US) | 2007-10-10 | — | — | EP | disclosed |
| US-7091216-B2 | Substituted furo[2,3-b]pyridine derivatives | MERCK & CO., INC. (US) | 2006-08-15 | — | — | US | disclosed |
| US-20050272763-A1 | Substituted furo[2,3-b]pyridine derivatives | MERCK SHARP & DOHME CORP. | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272763-A1 | Substituted furo[2,3-b]pyridine derivatives | CNR1, CNR2, FAAH | CNR1 1/4885CNR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.