Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11438943 | 1.00 | ALDH1A1 (0.86) | — | |
| Alcohol SCHEMBL2151440 | 1.00 | — | — | |
| Alcohol SCHEMBL27591403 | 1.00 | — | — | |
| Alcohol SCHEMBL10481768 | 1.00 | — | — | |
| Alcohol SCHEMBL11820598 | 1.00 | ALDH1A1 (0.86) | — | |
| Alcohol SCHEMBL29637683 | 1.00 | ALDH1A1 (0.86) | — | |
| Alcohol SCHEMBL48128 | 1.00 | — | — | |
| Alcohol SCHEMBL8470225 | 1.00 | — | — | |
| Alcohol SCHEMBL22616193 | 1.00 | ALDH1A1 (0.86) | — | |
| Alcohol SCHEMBL25268274 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809632-A2 | PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES USEFUL AS PDE-5 INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006046135-A2 | PYRAZOLO[4,3-D] PYRIMIDINE DERIVATIVES USEFUL AS PDE-5 INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-05-04 | — | — | WO | disclosed |