SCHEMBL5248589

SCHEMBL5248589

C=CCCCOC(=O)C(=C)C

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.58
THRB P10828 1/20 0.55
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 7/20 0.41
LMNA P02545 2/20 0.40
CYP3A4 P08684 3/20 0.39
MAPT P10636 3/20 0.39
USP2 O75604 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
RECQL P46063 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HPGD P15428 2/20 0.38
ABCC4 O15439 1/20 0.36
ATM Q13315 1/20 0.36
LPAR2 Q9HBW0 1/20 0.36
LPAR3 Q9UBY5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL27518086 0.96 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL809304 0.94 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
Trimethylammonium SCHEMBL28049823 0.93 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23322000 0.92 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321924 0.92 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321544 0.92 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23322287 0.92 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23322252 0.92 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23203417 0.92 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321555 0.92 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110054811-A A kind of rubber wear-resisting floor 常州瑞坦商贸有限公司 2019-07-26 CN claimed
CN-109942240-A A kind of preparation method of spontaneous heating conducting concrete 刘优 2019-06-28 CN claimed
CN-109824350-A A kind of preparation method of ceramics resistant brick 高阳 2019-05-31 CN claimed
CN-105891483-B A kind of preparation method of the unmarked electrochemical immunosensor based on graphene parcel polystyrene composite Nano ball 扬州大学 2017-11-14 CN claimed
CN-105175740-B A kind of preparation method of high workability esters polycarboxylate water-reducer 科之杰新材料集团有限公司 2017-08-25 CN claimed
EP-3819301-B1 PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP SHINETSU CHEMICAL CO (JP) 2025-08-06 EP disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
CN-114975939-A Water-based cathode slurry, cathode pole piece and lithium ion battery 武汉微美新材料科技有限公司 2022-08-30 CN disclosed
US-11377455-B2 Preparation of organosilicon compound having (meth)acryloyloxy group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-07-05 US disclosed
US-20210139515-A1 Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-05-13 US disclosed
EP-3819301-A1 PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP Shin-Etsu Chemical Co., Ltd. (JP) 2021-05-12 EP disclosed
CN-104649916-B Photocrosslinkable materials 罗利克有限公司 2020-12-01 CN disclosed
EP-0964878-B1 HYDROLYTICALLY STABLE RESINS FOR USE IN ANION-EXCHANGE CHROMATOGRAPHY DIONEX CORP (US) 2007-09-12 EP disclosed
EP-0964878-A4 HYDROLYTICALLY STABLE RESINS FOR USE IN ANION-EXCHANGE CHROMATOGRAPHY DIONEX CORP (US) 2004-12-22 EP disclosed
EP-0964878-A1 HYDROLYTICALLY STABLE RESINS FOR USE IN ANION-EXCHANGE CHROMATOGRAPHY DIONEX CORPORATION (US) 1999-12-22 EP disclosed
US-5936003-A RESIN SUPPORT PARTICLES AND ANION EXCHANGE COMPOUNDS ATTACHED WHEREIN THE ANION-EXCHANGE COMPOUNDS COMPRISE AN INTERNAL REACTIVE GROUP, WHICH MAY BE AN ESTER, KETONE OR AMIDE GROUP, AND A TERMINAL QUATERNARY AMMONIUM SALT WHICH FUNCTIONS AS AN DIONEX CORPORATION (US) 1999-08-10 US disclosed
US-5925253-A SYNTHETIC RESIN STATIONARY PHASE LINKED TO QUATERNIZED ANION-EXCHANGE SITES THROUGH REACTIVE GROUP AND ELONGATED LINKING ATOM CHAIN DIONEX CORPORATION (US) 1999-07-20 US disclosed
WO-1998039367-A1 HYDROLYTICALLY STABLE RESINS FOR USE IN ANION-EXCHANGE CHROMATOGRAPHY DIONEX CORPORATION (US) 1998-09-11 WO disclosed
US-4770968-A INCORPORATED RELEASE AGENT XEROX CORPORATION (US) 1988-09-13 US disclosed
US-3944347-A Contact lens having a hard center and soft, tough periphery E. I. DU PONT DE NEMOURS & CO. (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377455-B2 Preparation of organosilicon compound having (meth)acryloyloxy group H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR TSHR 1239/4885THRB 2877/4885POLB 1464/4885
US-20210139515-A1 Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR TSHR 1250/4885THRB 2844/4885POLB 1427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.