⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246035 | 0.93 | CHRM2 (0.43) | — | |
| SCHEMBL5245054 | 0.92 | CHRM2 (0.39) | — | |
| SCHEMBL6289595 | 0.91 | EPHX1 (0.42) | — | |
| SCHEMBL5247896 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL21066073 | 0.84 | — | — | |
| SCHEMBL16845049 | 0.79 | — | — | |
| SCHEMBL5953478 | 0.79 | — | — | |
| SCHEMBL20749780 | 0.78 | HTR2C (0.41) | — | |
| SCHEMBL31181399 | 0.78 | TSHR (0.42) | — | |
| SCHEMBL5246963 | 0.78 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164481-A | Methyl (3-methylaminopropyl) carbamate derivatives of ZL006-05 and pharmaceutically acceptable salts thereof and pharmaceutical application thereof | 苏州南医大创新中心 | 2023-12-05 | — | — | CN | claimed |
| CN-117586160-A | Sulfur-containing prodrug compound and medical application thereof | 中国药科大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-117164481-A | Methyl (3-methylaminopropyl) carbamate derivatives of ZL006-05 and pharmaceutically acceptable salts thereof and pharmaceutical application thereof | 苏州南医大创新中心 | 2023-12-05 | — | — | CN | disclosed |
| CN-117164481-A | Methyl (3-methylaminopropyl) carbamate derivatives of ZL006-05 and pharmaceutically acceptable salts thereof and pharmaceutical application thereof | 苏州南医大创新中心 | 2023-12-05 | — | — | CN | disclosed |
| CN-117164481-A | Methyl (3-methylaminopropyl) carbamate derivatives of ZL006-05 and pharmaceutically acceptable salts thereof and pharmaceutical application thereof | 苏州南医大创新中心 | 2023-12-05 | — | — | CN | disclosed |
| CN-116903588-A | Five-membered and six-membered compound, intermediate, preparation method, composition and application | 厦门市博瑞来医药科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116693411-A | Novel carbonyl lipid and lipid nanoparticle formulations for delivery of nucleic acids | 爱康泰生治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116368131-A | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-110799492-B | Novel carbonyl lipid and lipid nanoparticle formulations for delivery of nucleic acids | 爱康泰生治疗公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116284089-A | Fluoboric part cyanine fluorescent probe and preparation method and application thereof | 四川大学华西医院 | 2023-06-23 | — | — | CN | disclosed |
| CN-114258318-A | Aminopyrimidine amide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2022-03-29 | — | — | CN | disclosed |
| WO-2021158707-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2021-08-12 | — | — | WO | disclosed |
| CN-108349963-B | Sodium channel blockers | 株式会社大熊制药 | 2021-03-30 | — | — | CN | disclosed |
| CN-107205961-B | Prodrugs of phenolic TRPV1 agonists | 同心镇痛药物公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020120576-A1 | p38α AUTOPHOSPHORYLATION INHIBITORS | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2020-06-18 | — | — | WO | disclosed |
| CN-110799492-A | Novel carbonyl lipid and lipid nanoparticle formulations for delivery of nucleic acids | 爱康泰生治疗公司 | 2020-02-14 | — | — | CN | disclosed |
| CN-108349963-A | sodium channel blockers | 株式会社大熊制药 | 2018-07-31 | — | — | CN | disclosed |
| EP-1379598-B1 | UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS | BASF AG (DE) | 2007-09-12 | — | — | EP | disclosed |
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |