Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 11/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246035 | 0.98 | CHRM2 (0.43) | EPHX1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5248809 | 0.91 | — | — | |
| SCHEMBL5245054 | 0.84 | CHRM2 (0.39) | EPHX1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5247896 | 0.82 | — | — | |
| SCHEMBL31296577 | 0.82 | TSHR (0.50) | EPHX1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2746089 | 0.82 | TSHR (0.50) | EPHX1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2136691 | 0.82 | TSHR (0.50) | EPHX1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2139712 | 0.82 | TSHR (0.50) | EPHX1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5721317 | 0.82 | TSHR (0.50) | EPHX1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2059697 | 0.82 | TSHR (0.50) | EPHX1CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989219-A | Probenecid compounds for the treatment of inflammasome-mediated pulmonary diseases | 贝凯恩生物医疗技术有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-114173879-A | Methods of characterizing and utilizing agent-aggregate interactions | 怀特黑德生物医学研究所 | 2022-03-11 | — | — | CN | disclosed |
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |