Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.72 |
| ▸ | CA2 | P00918 | 5/20 | 0.65 |
| ▸ | CA1 | P00915 | 3/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16770420 | 0.95 | PTPN1 (0.66) | PTPN1CA2CA1CA12CA9 | |
| SCHEMBL3995785 | 0.94 | PTPN1 (0.65) | PTPN1CA2CA1CA12CA9 | |
| SCHEMBL111236 | 0.88 | ACE (0.76) | PTPN1CA2CA1ACEL3MBTL1 | |
| SCHEMBL528464 | 0.88 | ACE (0.76) | PTPN1CA2CA1ACEL3MBTL1 | |
| SCHEMBL111235 | 0.88 | ACE (0.76) | PTPN1CA2CA1ACEL3MBTL1 | |
| SCHEMBL10526607 | 0.87 | PTPN1 (0.70) | PTPN1CA2CA1CA12CA9 | |
| SCHEMBL4682004 | 0.87 | PTPN1 (0.70) | PTPN1CA2CA1CA12CA9 | |
| SCHEMBL4166657 | 0.87 | PTPN1 (0.70) | PTPN1CA2CA1CA12CA9 | |
| SCHEMBL2632872 | 0.86 | PTPN1 (0.74) | PTPN1CA2CA1CA12CA9 | |
| SCHEMBL8196220 | 0.86 | PTPN1 (0.74) | PTPN1CA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334962-B1 | PROCESS FOR THE PREPARATION OF ACYLPHENYLALANINES | AJINOMOTO KK (JP) | 2007-09-19 | — | — | EP | disclosed |
| US-RE34878-E | Hypoglycemic agent | AJINOMOTO CO., INC. (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0196222-B1 | HYPOGLYCEMIC AGENT | AJINOMOTO CO., INC. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-4816484-A | D-PHENYLALANINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1989-03-28 | — | — | US | disclosed |
| EP-0196222-A2 | Hypoglycemic agent | AJINOMOTO CO., INC. (JP) | 1986-10-01 | — | — | EP | disclosed |