SCHEMBL528464

SCHEMBL528464

O=C(N[C@H](Cc1ccccc1)C(=O)O)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACE P12821 2/20 0.76
PTPN1 P18031 2/20 0.75
CA2 P00918 2/20 0.71
CA1 P00915 1/20 0.71
GPR132 Q9UNW8 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.65
CTSL P07711 3/20 0.64
CTSS P25774 1/20 0.64
CTSK P43235 1/20 0.64
ITGB3 P05106 1/20 0.61
ITGA2B P08514 1/20 0.61
MEN1 O00255 1/20 0.61
ALDH1A1 P00352 1/20 0.61
KMT2A Q03164 1/20 0.61
CTRB1 P17538 3/20 0.61
MME P08473 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111236 1.00 ACE (0.76) ACEPTPN1CA2CA1GPR132
SCHEMBL111235 1.00 ACE (0.76) ACEPTPN1CA2CA1GPR132
SCHEMBL28419447 0.98 ACE (0.74) ACEPTPN1CA2CA1GPR132
SCHEMBL28419446 0.98 ACE (0.74) ACEPTPN1CA2CA1GPR132
Hydrochloric Acid SCHEMBL10622640 0.98 ACE (0.74) ACEPTPN1CA2CA1GPR132
SCHEMBL4357736 0.94 ACE (0.68) ACEPTPN1CA2CA1GPR132
SCHEMBL4356229 0.94 ACE (0.68) ACEPTPN1CA2CA1GPR132
SCHEMBL6857183 0.92 PTPN1 (0.69) ACEPTPN1CA2CA1GPR132
SCHEMBL10033681 0.92 PTPN1 (0.69) ACEPTPN1CA2CA1GPR132
SCHEMBL2632872 0.92 PTPN1 (0.74) ACEPTPN1CA2CA1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113912762-B Water-soluble near-infrared two-region macromolecular fluorescent probe and preparation method and application thereof 复旦大学 2023-02-10 CN claimed
CN-115433218-A Amphiphilic BODIPY compound NBDP modified by multi-site hexaethylene glycol and preparation method and application thereof 杭州师范大学 2022-12-06 CN claimed
CN-112929879-B NBDP clustering-based wireless sensor network malicious node detection method 电子科技大学 2022-05-03 CN claimed
CN-121397616-B Emergency equipment communication test method, device, equipment, medium and product 广州海格通信集团股份有限公司 2026-05-12 CN disclosed
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function Lee Moffitt Cancer Center and Research Institute, Inc. (US) 2026-03-03 US disclosed
CN-121471282-A Dimer type Aza-BODIPY base molecule and preparation method and application thereof 南京工业大学 2026-02-06 CN disclosed
CN-121248642-A Tumor blood vessel blocking type photodiagnosis and treatment molecule and preparation method and application thereof 南京工业大学 2026-01-02 CN disclosed
US-20260000710-A1 Novel Treatments for Cardiovascular Related Disease LA JOLLA INST FOR IMMUNOLOGY (US) 2026-01-01 US disclosed
CN-119583285-A OFDM signal receiving and processing system and method suitable for NAVDAT system 重庆邮电大学 2025-03-07 CN disclosed
CN-118725169-A Water-soluble near-infrared two-region chemiluminescent macromolecular fluorescent probe and preparation method and application thereof 安徽师范大学 2024-10-01 CN disclosed
CN-115334098-B Enterprise digital system based on industrial PaaS technology 中海油田服务股份有限公司 2024-09-10 CN disclosed
EP-0174358-A1 NOVEL DIASTEREOMER SALTS OF PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF AND PROCESS FOR THE SEPARATION OF OPTICALLY ACTIVE PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF ALKALOIDA VEGYéSZETI GYáR (HU) 1986-03-19 EP disclosed
WO-1985003932-A1 NOVEL DIASTEREOMER SALTS OF PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF AND PROCESS FOR THE SEPARATION OF OPTICALLY ACTIVE PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF ALKALOIDA VEGYÉSZETI GYÁR (HU) 1985-09-12 WO disclosed
EP-0036713-B1 ANGIOTENSIN CONVERTING ENZYME INHIBITORS UNIVERSITY OF MIAMI (US) 1984-01-18 EP disclosed
EP-0031877-B1 OPTICALLY ACTIVE 1,2-BIS-(DIPHENYLPHOSPHINO)-COMPOUNDS, METAL COMPLEXES CONTAINING THEM AS CHIRAL LIGANDS AND THEIR USE Degussa Aktiengesellschaft (DE) 1983-02-02 EP disclosed
EP-0023730-B1 CYCLOHEXYLCYCLOHEXANOATES, PROCESS FOR THEIR PREPARATION AND LIQUID-CRYSTAL MIXTURE CONTAINING THEM MERCK PATENT GmbH (DE) 1982-11-03 EP disclosed
US-4356324-A CHIRAL LIGANDS FOR RHODIUM HYDROGENATION CATALYSTS DEGUSSA AKTIENGESELLSCHAFT, A GERMAN CORP. (DE) 1982-10-26 US disclosed
EP-0036713-A2 Angiotensin converting enzyme inhibitors UNIVERSITY OF MIAMI (US) 1981-09-30 EP disclosed
EP-0031877-A1 Optically active 1,2-Bis-(diphenylphosphino)-compounds, metal complexes containing them as chiral ligands and their use Degussa Aktiengesellschaft (DE) 1981-07-15 EP disclosed
EP-0023730-A1 Cyclohexylcyclohexanoates, process for their preparation and liquid-crystal mixture containing them MERCK PATENT GmbH (DE) 1981-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260000710-A1 Novel Treatments for Cardiovascular Related Disease HLA-DRB1, APOL1, MICA ACE 1478/4885PTPN1 1519/4885CA2 4587/4885
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function CRBN, CD4, ICOS ACE 3749/4885PTPN1 118/4885CA2 1131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.