Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661632 | 0.97 | ALDH1A1 (0.55) | ALDH1A1LMNAGAAATMHPGD | |
| SCHEMBL3666959 | 0.93 | — | — | |
| SCHEMBL8288869 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNAGAAATMHPGD | |
| SCHEMBL17377715 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAGAAATMHPGD | |
| SCHEMBL4261207 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAGAAATMHPGD | |
| SCHEMBL4840666 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAGAAATMHPGD | |
| SCHEMBL11889662 | 0.83 | ALDH1A1 (0.58) | ALDH1A1LMNAGAAATMHPGD | |
| SCHEMBL8024247 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAGAAATMHPGD | |
| SCHEMBL9717393 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAGAAATMHPGD | |
| SCHEMBL24117774 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAGAAATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116183763-A9 | Impurity detection method of piracetam injection | 北京星昊盈盛药业有限公司 | 2024-01-05 | — | — | CN | claimed |
| US-11708344-B2 | Flavone derivatives for the treatment and prophylaxis of hepatitis B virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-07-25 | — | — | US | claimed |
| CN-116183763-A | Impurity detection method of piracetam injection | 北京星昊盈盛药业有限公司 | 2023-05-30 | — | — | CN | claimed |
| US-20230074887-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | HOFFMANN-LA ROCHE INC. (US) | 2023-03-09 | — | — | US | claimed |
| EP-3860984-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. Hoffmann-La Roche AG (CH) | 2021-08-11 | — | — | EP | claimed |
| CN-112912371-A | Flavone derivatives for treating and preventing hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2021-06-04 | — | — | CN | claimed |
| WO-2020070088-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2020-04-09 | — | — | WO | claimed |
| EP-2558449-B1 | NOVEL 3,3-DIMETHYL TETRAHYDROQUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2014-03-05 | — | — | EP | claimed |
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | claimed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | claimed |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2011-03-17 | — | — | US | claimed |
| EP-0669334-A1 | TRICYCLIC COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-30 | — | — | EP | claimed |
| EP-4729513-A1 | A-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | Nanjing Chempion Biotechnology Co., Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2025001687-A1 | Α-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | 南京桦冠生物技术有限公司 | 2025-01-02 | — | — | WO | disclosed |
| CN-117647600-A | Impurity detection method of piracetam injection | 华中药业股份有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-116183763-A9 | Impurity detection method of piracetam injection | 北京星昊盈盛药业有限公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-0457195-A2 | Peptides having endothelin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |
| US-4883797-A | CARDIOVASCULAR PROPERTIES; INCREASING CEREBRAL FLOW | FERRER INTERNACIONAL, S.A. (ES) | 1989-11-28 | — | — | US | disclosed |
| EP-0097340-A2 | Piperazine derivatives, a process for preparing them and pharmaceutical compositions | FERRER INTERNACIONAL, S.A. (ES) | 1984-01-04 | — | — | EP | disclosed |
| US-4341790-A | CEREBRAL CIRCULATORY, ATROPHY, AND AGING | A. NATTERMANN & CIE. GMBH (DE) | 1982-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708344-B2 | Flavone derivatives for the treatment and prophylaxis of hepatitis B virus disease | CCNE2, CCNE1, CCNT1 | ALDH1A1 455/4885LMNA 1778/4885GAA 1531/4885 |
| US-20230074887-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | CCNE2, CCNE1, CCNT1 | ALDH1A1 455/4885LMNA 1778/4885GAA 1531/4885 |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | PDE4A, PDE4B, PDE4D | ALDH1A1 1228/4885LMNA 2956/4885GAA 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.