Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544946 | 0.82 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL3544952 | 0.82 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL5302841 | 0.78 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL5301809 | 0.78 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL5252296 | 0.78 | DGAT1 (0.73) | DGAT1 | |
| SCHEMBL5302124 | 0.76 | DGAT1 (0.71) | DGAT1 | |
| SCHEMBL5298516 | 0.76 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL5248671 | 0.75 | DGAT1 (0.64) | DGAT1 | |
| SCHEMBL18236237 | 0.75 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL31263996 | 0.74 | AURKA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833806-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006064189-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |