Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.55 |
| ▸ | CCND1 | P24385 | 4/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086006 | 0.79 | CDK4 (0.55) | CDK4CCND1HTR6KMT2APLAU | |
| SCHEMBL30201821 | 0.79 | CDK4 (0.55) | CDK4CCND1HTR6KMT2APLAU | |
| SCHEMBL6087404 | 0.79 | HTR6 (0.56) | CDK4CCND1HTR6KMT2APLAU | |
| SCHEMBL31257964 | 0.79 | CDK4 (0.55) | CDK4CCND1HTR6KMT2APLAU | |
| SCHEMBL17454529 | 0.79 | CDK4 (0.55) | CDK4CCND1HTR6KMT2APLAU | |
| SCHEMBL31257954 | 0.79 | HTR6 (0.56) | CDK4CCND1HTR6KMT2APLAU | |
| SCHEMBL6086178 | 0.79 | CDK4 (0.55) | CDK4CCND1HTR6KMT2APLAU | |
| SCHEMBL30577034 | 0.79 | CDK4 (0.55) | CDK4CCND1HTR6KMT2APLAU | |
| SCHEMBL6086530 | 0.79 | CDK4 (0.55) | CDK4CCND1HTR6KMT2APLAU | |
| SCHEMBL6086394 | 0.76 | CDK4 (0.52) | CDK4CCND1HTR6KMT2APLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |